Pinealon is a synthetic tripeptide (Glu-Asp-Arg, EDR) from the Khavinson short-peptide series. The EDR sequence was characterized from Cortexin, a polypeptide preparation derived from bovine cerebral cortex. It has the molecular formula C15H26N6O8, a molecular weight of approximately 418.40 g/mol, CAS number 175175-23-2. Its sequence is Glu-Asp-Arg (EDR). EDR is reported in the peer-reviewed literature to bind DNA at promoter-region motifs of several genes and to modulate MAPK/ERK signalling in cultured cells. These interactions are described from in-vitro and modeling studies. Supplied as a white to off-white lyophilized powder, stored refrigerated at 2–8 °C. This product is strictly for research purposes only.
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